NA2R® is a clinically proven tryptophan-rich egg protein hydrolysate engineered to raise brain serotonin — naturally, measurably, and at doses that work in your formulation.
Serotonin synthesis starts with tryptophan. NA2R® is engineered with a uniquely high Trp:LNAA ratio — so more tryptophan crosses the blood-brain barrier, and more serotonin gets made.
NA2R® is an enzymatic hydrolysate of hen egg white protein. Its amino acid composition is precision-engineered to maximise the tryptophan-to-large neutral amino acid (Trp:LNAA) ratio — limiting competition at the transport site that matters most.
Tryptophan competes with other LNAAs at the LAT1 transporter on the blood-brain barrier. NA2R®'s low-LNAA matrix clears the competition — measurably raising the plasma Trp:LNAA ratio by up to 48% within 90 minutes of consumption.
More brain tryptophan triggers the tryptophan → 5-HTP → serotonin pathway. Clinical outcomes include balanced mood, reduced fatigue, sharper focus, faster reaction time, and improved sleep quality — at regulatory-approved doses.
NA2R® is supplied as a precision-milled powder ready for integration into virtually any delivery format. Clean-label, allergen-declared, globally compliant.
RTDs, powdered drink mixes, and functional shots. Mixes cleanly with minimal organoleptic impact. Effective at low-volume dosing.
Standard encapsulation and tablet compression. Precise dosing and excellent flowability for high-throughput supplement manufacturing.
Bars, cereals, snacks, and fortified food products. Performs cleanly across food matrices. Clean-label compatible for modern brand positioning.
Recovery stacks, pre-sleep formulas, nootropic blends. WADA-certified doping-free — safe for elite athlete products and competitive supplement brands.
NA2R® is backed by 7 peer-reviewed studies published in leading scientific journals. These are the headline findings.
A dose-dependent increase in plasma Trp:LNAA ratio — the gold-standard marker for brain tryptophan availability. A casein control beverage decreased the ratio by 9% in the same study.
Randomised double-blind controlled trial: NA2R® produced a significant shift toward positive emotional processing and prevented the wellbeing decline observed in the placebo group.
19-day parallel RCT: chronic NA2R® treatment improved emotional bias, increased mental energy levels, accelerated reaction times, and improved sustained attention throughout the treatment period.
Commission Regulation approved. Max 1,000 mg/day in food supplements.
New Dietary Ingredient notification filed with FDA. No objections received.
Certified Halal — compliant for use in Islamic dietary products worldwide.
Kosher certified for products complying with Jewish dietary law.
Doping-free certified. Safe for use in elite sports nutrition products.
Request a sample of NA2R® or download our technical data sheet to begin the conversation with our team.
USA: NA2R® is a New Dietary Ingredient (NDI) notified to the U.S. Food and Drug Administration (FDA), with a no-objection ("no questions" letter) response.
Note: NA2R® is an egg-derived product and therefore should be considered as a potential allergen.
Regulations may vary according to the country. Always check the local legislation regarding the claims and usage of this product.
These statements have not been evaluated by the Food and Drug Administration. This ingredient is not intended to diagnose, treat, cure, or prevent any disease.